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Diabetes isn’t the only factor that can lead to dementia. Heart conditions, excessive alcohol consumption, urinary tract infections, and many other physical causes can also contribute. If you are experiencing memory loss, it’s important to consult your doctor for a thorough evaluation.

In this article, you will learn how high blood sugar impacts brain health, explore lifestyle factors, and find out what you can do to protect your loved ones and yourself from these conditions.

Exploring the Complex Relationship Between Diabetes and Dementia

Recent research has increasingly linked diabetes to dementia, shedding light on how high blood sugar levels may contribute to the death of nerve cells in the brain.

diabetes and dementia

Key questions remain:

  • Does diabetes cause dementia?
  • Does dementia cause diabetes?
  • Are specific lifestyle choices responsible for predisposing individuals to both conditions?
  • Can we prevent either condition?
  • Are family caregivers of individuals with dementia at higher risk for developing diabetes or dementia themselves?

Family caregivers, in particular, are eager for answers as they care for aging loved ones. Many would gladly adopt changes in habits, activity, or diet to prevent these diseases in their senior relatives or themselves. However, what do we truly know about these connections, and what remains speculative?

Increased Brain Tangles Found in Diabetics

A recent study published in Neurology revealed that individuals diagnosed with Type 2 Diabetes exhibited a higher number of brain tangles, even without a dementia diagnosis. Researchers suggest that an increase in tangles may elevate the risk of developing Alzheimer’s disease.

However, the study’s authors caution that the presence of more tangles in those with diabetes does not necessarily indicate that diabetes or high blood sugar is the cause of these brain deposits. Obesity, which is common among people with Type 2 Diabetes, may also play a role in the formation of tangles.

Can High Blood Sugar Lead to Tangles?

Chronic high blood sugar might impact the circulatory system, particularly in the brain, potentially leading to the accumulation of tangles. Researchers recommend better blood sugar control to prevent tangle formation. One theory suggests that sugar molecules attach to proteins in the blood, resulting in tangles through a process called glycation.

Additionally, individuals with diabetes face twice the risk of developing dementia, although the exact cause remains unknown. Another contributing factor to brain deterioration and tangle formation could be widespread inflammation in the body.

sugar causes diabetes

Alzheimer’s – the New Type 3 Diabetes?

Emerging research has revealed striking similarities between the brains of individuals with Alzheimer’s disease and those with diabetes. Upon closer examination, researchers discovered that insulin resistance and deficiency in the brain are precursors to Alzheimer’s neurodegeneration.

One study delved deeper into this connection, despite conflicting data regarding the impact of metabolic syndrome and obesity on neurodegeneration, suggesting that insulin may not be the sole factor.

By analyzing post-mortem brains of Alzheimer’s patients, researchers identified various abnormalities, leading them to conclude that the term “type 3 diabetes” accurately describes Alzheimer’s as a brain-specific form of diabetes.

Insulin Produced by the Brain, Too

Researchers from Brown Medical School discovered that the brain produces insulin in addition to the pancreas. While obesity contributes to insulin resistance in the brain, its role is considered modest. Type 2 diabetes is also a factor, not directly causing Alzheimer’s disease but potentially accelerating its progression.

Brain impairment due to insulin resistance is further influenced by inflammation, oxidative stress, and cell dysfunction. These findings support the concept of “type 3 diabetes,” suggesting a specific form of diabetes that affects the brain. Remarkably, cognitive improvements have been observed in individuals treated with intranasal insulin.

insulin for diabetes

Continual Investigation: Blood Sugar Regulation and Dementia

Recent findings suggest that Alzheimer’s disease may initiate without hyperglycemia in the brain, yet insulin resistance plays a crucial role in its progression.

Individuals with insulin resistance, such as those with Type 2 diabetes, face a 50-65% higher risk of developing Alzheimer’s disease.

Furthermore, studies have shown a correlation between poorly controlled blood sugar levels and diminished cognitive performance on administered tests. Further research is needed to determine if cognitive function can be enhanced through disease management strategies aimed at controlling blood sugar levels.

senior with her granddaughter eating sweets

Can Dietary Changes Enhance Cognitive Function?

Available data suggests a notable connection between insulin resistance, diabetes, blood sugar control, and dementia, with obesity exacerbating the issue.

Taking charge of blood sugar levels, achieving a healthy weight, staying physically active, and being vigilant about diabetes risk factors through timely testing may prevent or slow down the progression of some dementia cases.

Adopting an appropriate diet and lifestyle can reduce the risk of both dementia and diabetes. Here are some recommendations to integrate into daily life:

  • Embrace a diverse, nutritious diet.
  • Engage in regular physical activity.
  • Keep the mind stimulated.
  • Prioritize nutrient-dense foods rich in vitamins, including vitamin D, calcium, B vitamins, and antioxidants.
  • Opt for heart-healthy food choices, aligning with principles of the Mediterranean diet while steering clear of high-fat foods.
  • Limit intake of sugary foods and beverages.
  • Avoid processed meats containing nitrates, such as bacon, sausage, hot dogs, lunch meat, and ham.

Furthermore, emerging research suggests that “junk” food might exacerbate insulin resistance in the brain, worsening Alzheimer’s disease, often referred to as type 3 diabetes.

While diabetes doesn’t directly cause Alzheimer’s, they share a common link through insulin resistance.

healthy seniors no diabetes and dementia

As ongoing investigations shed more light on the intricate relationship between overall health and dementia, it underscores the importance of adopting healthier lifestyles. Encouragingly, it’s never too late to start making positive changes, a sentiment particularly relevant for family caregivers supporting their senior loved ones in prioritizing brain health.

Take charge of your brain health today! Start by embracing a diverse, nutritious diet, staying physically active, and keeping your mind stimulated. Prioritize foods rich in essential vitamins and antioxidants while avoiding sugary and processed options. If you have questions or need help, feel free to reach out to me, Senior Care of Sacramento.  Together, let’s nourish our bodies and minds for a healthier tomorrow.

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